Acceptable Daily Intake (ADI) Reference
EFSA-evaluated acceptable daily intake (ADI) limits for 44 food additives, compiled from European Food Safety Authority opinions and FDA guidance. ADI values indicate how much of an additive can be safely consumed per day over a lifetime; see our methodology for sources and caveats.
Health Information Notice
ADI values are from EFSA evaluations and are for informational purposes only. Individual dietary needs vary. Consult a healthcare professional for personalized dietary guidance.
How to Read ADI Values
ADI is expressed in mg per kg of body weight per day. For example, an ADI of 5 mg/kg bw/day means a 70 kg (154 lb) adult can safely consume up to 350 mg daily. Multiply the ADI by your weight in kg to find your personal daily limit.
Antioxidant
| Additive | ADI (mg/kg bw/day) |
|---|---|
| Erythorbic Acid | 6 |
| Sodium Erythorbate | 6 |
Color Additive
| Additive | ADI (mg/kg bw/day) |
|---|---|
| Ammonia Caramel | 100 |
| Blue 2 (Indigo Carmine) | 5 |
| Brilliant Black Bn | 5 |
| Caustic Sulphite Caramel | 300 |
| Indigotine | 5 |
| Plain Caramel | 300 #not the ADI of E150a alone but an ADI shared by the four E150-a,b,c,d- |
| Sulphite Ammonia Caramel | 300 |
Emulsifier
Food Additive
| Additive | ADI (mg/kg bw/day) |
|---|---|
| Calcium Bisulphite | 0.7 |
| Calcium Sulphite | 0.7 |
| Patent Blue V | 5 |
| Potassium Bisulphite | 0.7 |
Preservative
| Additive | ADI (mg/kg bw/day) |
|---|---|
| Benzoic Acid | 5 |
| Calcium Benzoate | 5 |
| Potassium Benzoate | 5 |
| Potassium Metabisulphite | 0.7 |
| Potassium Nitrate | 3.7 |
| Potassium Sorbate | 3 |
| Sodium Benzoate | 5 |
| Sodium Bisulphite | 0.7 |
| Sodium Metabisulfite | 0.7 |
| Sodium Metabisulphite | 0.7 |
| Sodium Nitrate | 3.7 |
| Sodium Sulphite | 0.7 |
| Sorbic Acid | 3 |
| Sulphur Dioxide | 0.7 |
Processing Aid
| Additive | ADI (mg/kg bw/day) |
|---|---|
| Propylene Glycol | 25 |
Sweetener
| Additive | ADI (mg/kg bw/day) |
|---|---|
| Aspartame | 40 |
| Stevia (Steviol Glycosides) | 4 |
| Steviol Glycosides | 4 |
Thickener
| Additive | ADI (mg/kg bw/day) |
|---|---|
| Beta-Cyclodextrine | 5 |
| Carrageenan | 75 |
Understanding Acceptable Daily Intake
The Acceptable Daily Intake (ADI) is the cornerstone of food additive safety evaluation. Established by the European Food Safety Authority (EFSA) and the Joint FAO/WHO Expert Committee on Food Additives (JECFA), ADI values represent the amount of a substance that can be consumed every day for a lifetime without appreciable health risk.
ADI values are derived from the most sensitive toxicological endpoint observed in animal studies. The No Observed Adverse Effect Level (NOAEL) — the highest dose at which no adverse effects are seen — is divided by a safety factor (typically 100) to account for species differences and human variability. This conservative approach means that actual harmful doses are usually far higher than the ADI.
Why ADI Matters for Consumers
While most people never consume enough of any single additive to approach the ADI, certain populations may be at higher risk of exceeding safe limits. Children, because of their lower body weight, can reach ADI thresholds more quickly. People who consume large quantities of processed foods containing multiple additives may also have higher cumulative exposure.
EFSA periodically re-evaluates ADI values as new scientific evidence emerges. Recent re-evaluations have led to reduced ADIs for some additives, including certain food colorings, as more refined toxicological data becomes available.
Frequently Asked Questions
What is Acceptable Daily Intake (ADI)?
ADI is the amount of a food additive that can be consumed daily over a lifetime without appreciable health risk. It is expressed in milligrams per kilogram of body weight per day (mg/kg bw/day). ADI values are set by safety authorities like EFSA (European Food Safety Authority) after reviewing toxicological studies.
How is ADI calculated?
ADI is typically derived by dividing the No Observed Adverse Effect Level (NOAEL) from animal studies by a safety factor of 100. This safety factor accounts for differences between species (factor of 10) and variation within the human population (factor of 10). Some additives use additional safety factors if data is limited.
Does exceeding the ADI mean immediate harm?
No. The ADI is designed with large safety margins. Occasionally exceeding the ADI is not expected to cause health effects. The ADI represents the level that is safe for daily consumption over an entire lifetime. Concern arises when ADI is consistently exceeded over long periods.
Why do some additives show "Not specified" for ADI?
When EFSA assigns "ADI not specified" or "Not limited," it means the additive is considered so safe at current usage levels that setting a numerical limit is unnecessary. This is typically reserved for substances with very low toxicity or those that are natural components of food.