Flavor Enhancer · EU 621

Monosodium Glutamate

FDA status: Approved. EU: Approved. No U.S. state has enacted a specific ban yet.

Caution
Score 2 of 5
Monosodium Glutamate: 2/5 (Caution)

According to the U.S. Food and Drug Administration, Monosodium Glutamate is FDA-approved, and no U.S. state has moved to restrict it independently of federal policy. Its composite safety score is 2 out of 5 (Caution), and the European Union separately classifies it as approved. By tracked product count it ranks #16 of 417.

  • #16 of 417 by tracked product prevalence

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The verdict

Monosodium Glutamate is FDA-approved, and no U.S. state has moved to restrict it. By Open Food Facts product count it sits #16 of 417 among additives with tracked product presence (96th percentile).

2/5
Caution
Approved
FDA status
#16 of 417
product-prevalence rank
0
state regulations

Product-footprint and regulatory snapshot

Monosodium Glutamate: 2,745 tracked U.S. products (common band, #16 of 417) frame how often this additive appears on shelves.

Property Value Source
Tracked Products 2,745 · #16 of 417 Open Food Facts (US)
FDA Status Approved FDA SAFFA
EU Status Approved EC 1333/2008
E-Number 621 EU additive register
CAS Number - CAS Registry
Category Flavor Enhancer FDA functional class
Composite Safety Score 2 / 5 (Caution) PlainIngredients methodology
EFSA ADI Not established EFSA scientific opinion
U.S. State Actions 0 states State legislative records

Values reflect official agency classifications as published by the U.S. Food and Drug Administration and the European Union's regulatory framework. See our methodology for scoring details.

What is Monosodium Glutamate?

MONOSODIUM GLUTAMATE -MSG, also known as sodium glutamate- is the sodium salt of glutamic acid, one of the most abundant naturally occurring non-essential amino acids.

Health Concerns

  • EFSA evaluation: Re‐evaluation of glutamic acid -E 620-, sodium glutamate -E 621-, potassium glutamate -E 622-, calcium glutamate -E 623-, ammonium glutamate -E 624- a. EFSA overexposure risk: high. Flagged by ANSES (French food safety agency) as additive of interest

Common Uses

Savory foods, snacks, processed meals

Shelf-footprint peer axes

Nationwide peers for a common OFF footprint

Nearest OFF product-count peers (2,745 tracked here); safety-score column omitted on prevalence-led pages.

Nearest OFF product count to 2,745

Nearest other additives by Open Food Facts product count (floored at ≥50).

8 peers

Frequently Asked Questions

Is Monosodium Glutamate safe to consume?

Monosodium Glutamate scores 2/5 (Caution). FDA status is Approved. On the Open Food Facts U.S. sample it is a common additive (2,745 tracked products, #16 of 417), so product footprint, not just the score label, frames how widely a shopper will meet it.