FDA Status
Approved
Monopotassium Glutamate (622) is a food additive additive holding a composite safety score of 4 out of 5 (Low Risk). The U.S. Food and Drug Administration currently classifies it as Approved, while the European Union lists it as Approved. This ingredient appears in approximately 5 tracked food products across our database. It is most commonly used as Various processed foods.
No U.S. state has enacted specific legislation targeting Monopotassium Glutamate to date, keeping federal FDA classification as the operative standard. State-level food safety legislation remains active nationally, and that picture may shift as new bills advance.
Peer-reviewed research has flagged 1 distinct area of health concern for Monopotassium Glutamate, which factors directly into the assigned safety score. The European Food Safety Authority has published an evaluation dated 2015-01-20. All figures above draw on FDA SAFFA inventory records, EU food additive regulation (EC) No 1333/2008, EFSA scientific opinions where published, and legislative records from individual U.S. states.
Regulatory Snapshot
| Property | Value | Source |
|---|---|---|
| FDA Status | Approved | FDA SAFFA |
| EU Status | Approved | EC 1333/2008 |
| E-Number | 622 | EU additive register |
| CAS Number | — | CAS Registry |
| Category | Food Additive | FDA functional class |
| Composite Safety Score | 4 / 5 (Low Risk) | PlainIngredients methodology |
| EFSA ADI | Not established | EFSA scientific opinion |
| U.S. State Actions | 0 states | State legislative records |
| Tracked Products | 5 | Open Food Facts (US) |
Values reflect official agency classifications as published by the U.S. Food and Drug Administration and the European Union's regulatory framework. See our methodology for scoring details.
4.0 / 5
Composite Safety Low Risk
Safety Score: 4 out of 5
Safety Rating 80.0%
EU Status
Approved
622
U.S. State Regulations
0 states
None enacted
Safety Assessment
Monopotassium Glutamate receives a safety score of 4/5 (Low Risk) based on a composite analysis of FDA regulatory status, EU approval, scientific literature on health effects, and state-level legislative actions. The FDA has approved Monopotassium Glutamate for use in food products under specified conditions.
Research has identified 1 area of health concern associated with Monopotassium Glutamate. Consumers with specific health conditions should consult a healthcare provider before consuming products containing this ingredient.
What is Monopotassium Glutamate?
Monopotassium Glutamate is a food additive (622) classified as food additive.
Health Concerns
- EFSA evaluation: Scientific Opinion on the safety of the change in the production method of L-glutamic acid -E620-, monosodium L-glutamate -E621-, monopotassium L-glut. Flagged by ANSES (French food safety agency) as additive of interest
Common Uses
Various processed foods
Frequently Asked Questions
Is Monopotassium Glutamate safe to consume?
Monopotassium Glutamate has a safety score of 4/5 (Low Risk). It is approved by the FDA for use in food. As with all food additives, moderation is advisable.
What is Monopotassium Glutamate used for in food?
Monopotassium Glutamate is commonly used as: Various processed foods. It belongs to the Food Additive category of food additives.
Is Monopotassium Glutamate banned in any US states?
Currently, no US states have enacted specific bans or regulations targeting Monopotassium Glutamate. However, state food safety legislation is evolving rapidly.
What is the difference between FDA and EU regulation of Monopotassium Glutamate?
The FDA classifies Monopotassium Glutamate as "Approved", while the EU status is "Approved" (622). The FDA and EU use separate evaluation frameworks — the EU often applies the precautionary principle, sometimes banning additives that remain approved in the US. Always check both jurisdictions when evaluating food additive safety.
What health concerns are associated with Monopotassium Glutamate?
Research has identified the following health concerns for Monopotassium Glutamate: EFSA evaluation: Scientific Opinion on the safety of the change in the production method of L-glutamic acid -E620-, monosodium L-glutamate -E621-, monopotassium L-glut. Flagged by ANSES (French food safety agency) as additive of interest. These findings inform its safety score of 4/5. Consult a healthcare provider for personalized guidance, especially if you have pre-existing conditions.
How is the safety score for Monopotassium Glutamate calculated?
The safety score of 4/5 for Monopotassium Glutamate is a composite assessment based on FDA regulatory status, EU approval status, published scientific research on health effects, and state-level legislative actions. A score of 1 means "Banned / Avoid" and 5 means "Generally Safe." The score is updated as new regulatory actions or scientific evidence emerge.
Explore PlainIngredients
Related Data Sources
Data Sources
- FDA Substances Added to Food (SAFFA) Inventory
- EU Food Additive Regulations (EC) No 1333/2008
- State food safety legislation and bill records
Related Resources
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Read our methodology — how this data is sourced, computed, and verified.
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Data sourced from official EWG, FDA GRAS, and ingredient toxicology databases. See our methodology for details. Retrieved and formatted by PlainIngredients Editorial