Flavor Enhancer · CAS 4691-65-0 · EU E631
Disodium Inosinate
FDA status: GRAS. EU: Approved. No U.S. state has enacted a specific ban yet.
According to the U.S. Food and Drug Administration, Disodium Inosinate is classified GRAS by the FDA, and no U.S. state has moved to restrict it independently of federal policy. Its composite safety score is 4 out of 5 (Low Risk), and the European Union separately classifies it as approved. By tracked product count it ranks #30 of 417.
- #30 of 417 by tracked product prevalence
The verdict
Disodium Inosinate is classified GRAS by the FDA, and no U.S. state has moved to restrict it. By Open Food Facts product count it sits #30 of 417 among additives with tracked product presence (93rd percentile).
- 4/5
- Low Risk
- GRAS
- FDA status
- #30 of 417
- product-prevalence rank
- 0
- state regulations
Product-footprint and regulatory snapshot
Disodium Inosinate: 1,685 tracked U.S. products (common band, #30 of 417) frame how often this additive appears on shelves.
| Property | Value | Source |
|---|---|---|
| Tracked Products | 1,685 · #30 of 417 | Open Food Facts (US) |
| FDA Status | GRAS | FDA SAFFA |
| EU Status | Approved | EC 1333/2008 |
| E-Number | E631 | EU additive register |
| CAS Number | 4691-65-0 | CAS Registry |
| Category | Flavor Enhancer | FDA functional class |
| Composite Safety Score | 4 / 5 (Low Risk) | PlainIngredients methodology |
| EFSA ADI | Not established | EFSA scientific opinion |
| U.S. State Actions | 0 states | State legislative records |
Values reflect official agency classifications as published by the U.S. Food and Drug Administration and the European Union's regulatory framework. See our methodology for scoring details.
What is Disodium Inosinate?
Nucleotide enhancer synergistic with MSG.
Health Concerns
- Safe. Same gout precaution.
Common Uses
Shelf-footprint peer axes
Nationwide peers for a common OFF footprint
Nearest OFF product-count peers (1,685 tracked here); safety-score column omitted on prevalence-led pages.
Nearest OFF product count to 1,685
Nearest other additives by Open Food Facts product count (floored at ≥50).
Frequently Asked Questions
Is Disodium Inosinate safe to consume?
Disodium Inosinate scores 4/5 (Low Risk). FDA status is GRAS. On the Open Food Facts U.S. sample it is a common additive (1,685 tracked products, #30 of 417), so product footprint, not just the score label, frames how widely a shopper will meet it.
What is Disodium Inosinate used for in food?
Disodium Inosinate shows up as Chips, instant noodles, sauces in the Flavor Enhancer class, and the OFF sample puts it in the common footprint band (1,685 products).
Where does Disodium Inosinate sit among food additives PlainIngredients tracks?
Among additives with at least one tracked product, it ranks #30 of 417 by Open Food Facts product count. See /methodology#corpus-placement for the ranking bases.
What is the difference between FDA and EU regulation of Disodium Inosinate?
The FDA classifies Disodium Inosinate as "GRAS" while the EU status is "Approved" (E631). The EU often applies the precautionary principle, sometimes restricting additives that remain approved in the US.
What health concerns are associated with Disodium Inosinate?
Research has identified the following health concerns for Disodium Inosinate: Safe. Same gout precaution.. These findings inform its safety score of 4/5. Consult a healthcare provider for personalized guidance, especially if you have pre-existing conditions.