Food Additive · CAS 5996-22-5 · EU 623
Calcium Diglutamate
FDA status: Approved. EU: Approved. No U.S. state has enacted a specific ban yet.
According to the U.S. Food and Drug Administration, Calcium Diglutamate is FDA-approved, and no U.S. state has moved to restrict it independently of federal policy. The European Union separately classifies it as approved.
The verdict
Calcium Diglutamate is FDA-approved, and no U.S. state has moved to restrict it.
- 4/5
- Low Risk
- Approved
- FDA status
- Approved
- EU status
- 0
- state regulations
Identified by CAS number, not shelf prevalence
Calcium Diglutamate: no OFF product match; CAS 5996-22-5 is the lead registry handle on this row.
| Property | Value | Source |
|---|---|---|
| CAS Number | 5996-22-5 | CAS Registry |
| FDA Status | Approved | FDA SAFFA |
| EU Status | Approved | EC 1333/2008 |
| E-Number | 623 | EU additive register |
| Category | Food Additive | FDA functional class |
| Composite Safety Score | 4 / 5 (Low Risk) | PlainIngredients methodology |
| EFSA ADI | Not in our EFSA data | EFSA scientific opinion |
| U.S. State Actions | 0 states | State legislative records |
| Tracked Products | Not yet tracked | Open Food Facts (US) |
Values reflect official agency classifications as published by the U.S. Food and Drug Administration and the European Union's regulatory framework. See our methodology for scoring details.
Calcium Diglutamate, explained
Calcium Diglutamate is a food additive (623) classified as food additive.
Health Concerns
- EFSA evaluation: Scientific Opinion on the safety of the change in the production method of L-glutamic acid -E620-, monosodium L-glutamate -E621-, monopotassium L-glut. Flagged by ANSES (French food safety agency) as additive of interest
Common Uses
Catalog-profile peer axes
How Calcium Diglutamate compares to its catalog-profile peers nationwide
Product-count (0) and safety-score (4/5) peer columns, disjoint link sets.
Score 4/5 peers (≥50 OFF products)
Nearest other additives by PlainIngredients safety score (floored at ≥50 tracked products), distinct from the count row.
Frequently Asked Questions
Is Calcium Diglutamate safe to consume?
Calcium Diglutamate scores 4/5 (Low Risk). FDA status is Approved. No OFF product match yet; the distinctive registry handle is CAS 5996-22-5, so this page leads with the chemical identity row rather than a shelf-prevalence claim.
What is Calcium Diglutamate used for in food?
Calcium Diglutamate (CAS 5996-22-5) is catalogued for Various processed foods (Food Additive); OFF has not matched a U.S. product row yet.
What health concerns are associated with Calcium Diglutamate?
Research has identified the following health concerns for Calcium Diglutamate: EFSA evaluation: Scientific Opinion on the safety of the change in the production method of L-glutamic acid -E620-, monosodium L-glutamate -E621-, monopotassium L-glut. Flagged by ANSES (French food safety agency) as additive of interest. These findings inform its safety score of 4/5. Consult a healthcare provider for personalized guidance, especially if you have pre-existing conditions.